The Quest to Cure Neurodegenerative Diseases

We all play a role in progress.

Over 8 million Americans live with neurodegenerative diseases, a group of conditions where the brain and nervous system deteriorate over time. Meet some of the biotech innovators working to develop new medicines to better treat—and even cure—these diseases.


This video features:

Eric Green

CEO

Trace Neuroscience

Dan O’Connell

Board Member & CEO

Acumen Pharmaceuticals

Sagar Vaidya

Chief Medical Officer

Cerevance

Eric Siemers

Chief Medical Officer

Acumen Pharmaceuticals

Craig Thompson

CEO

Cerevance

Mike Crackower

Chief Science Officer

Ventus Therapeutics

Paul Bolno

CEO

Wave Life Sciences

Over 8 million Americans live with neurodegenerative diseases, a group of conditions where the brain and nervous system deteriorate over time. These diseases, such as Alzheimer's, Parkinson's, ALS, and Huntington's, erode memory, mobility, and independence. People lose the ability to care for themselves and require a lot of support from caregivers.

But there is hope.

Many small biotech companies, including mine, are working on remarkable new technologies that we hope will someday allow us to treat and even cure neurodegenerative diseases. And there's a good chance you're helping us. Here's how.

If you're saving for retirement, as millions of working Americans are, there's a good chance some of your savings is in biotechnology and maybe even indirectly in my company. So thank you.

I know my investors are investing for their financial security and hope my product will be profitable. I hope so too. But profitable doesn't mean unaffordable thanks to insurance.

Insurance is possible because you and most Americans pay premiums. Our premiums make it possible for novel medicines to be both profitable and affordable. Only 8% of what we pay each month in insurance premiums goes towards novel branded medicines, creating incentives for investment in work like ours. So thank you and thanks to everyone who makes that possible.

But insurance in America doesn't always do what it promises. Some patients can't afford their medicines because of unaffordable high out-of-pocket costs. Congress is talking about capping those costs, which is the right idea. We certainly aren't inventing new medicines for anyone to be denied access to them.

Unfortunately, some people, including some members of Congress, think the way to help patients afford treatment is by letting the government control the prices of novel medicines. The problem is that price controls drive investors away. That's the case, not only in biotechnology, but in any industry.

If the reward for successfully developing a medicine is a government price control, I know my investors will invest elsewhere. I can't blame them. They are looking out for their hard-earned savings.

And price controls on novel medicines won't even save America money because what's special about medicines is they go generic. Novel medicines are branded until their patents expire. After that, they drop in price and cost America very little, but they still keep us healthy and out of hospitals.

If we stop investing in the pursuit of treatments and cures for neurodegenerative diseases, the burden on the healthcare system will grow as more patients require hospital-based care that offers limited hope. And those costs only climb—hospitals never go generic.

If we stop investing, millions of Americans will go on suffering, missing work, relying on caregivers. And our insurance premiums, which largely go to pay for hospitals and seeing doctors, will continue to climb.

So let's hope that Congress does not resort to price controls that turn investors away from research like ours, but instead caps out-of-pocket costs for patients. Insurance reform is the solution that will allow all of us—by investing, paying premiums, and doing science—to create new affordable medicines together.

So again, thank you. Thank you for your support, for helping to make breakthroughs by companies like ours possible. Thank you for helping us strive to bring new treatments to people who desperately need them. Thank you for being part of the massive team effort to build a healthier, happier, and more productive future.

And every time you check your retirement account or see that insurance deduction on your paycheck, we hope you don't just see numbers, but the promise of scientific progress. We hope that you'll see the brighter, healthier future that you are helping to build.

So again, thank you.